Study on the application of Vitamin B12 additive in feed and its production process innovation

       1· The application of Vitamin B12 additive in feed

　　With the rapid development of China's aquaculture industry, the demand for aquaculture feed in China has been increasing, vitamin additives as an essential component of feed, the demand is also rising. In order to obtain high quality vitamin additives for aquaculture, appropriate equipment and processes are needed, which is the key to the sustainable development of the feed industry and aquaculture industry. Vitamin B12 participates in the metabolic activity of a variety of substances in the body of livestock, poultry and fish in the form of coenzyme. Vitamin B12 not only participates in the metabolism of carbon group in the body of livestock, poultry and fish, but also participates in the synthesis of nucleic acid and protein of livestock, poultry and fish, which promotes the development and maturation of cells and speeds up the weight gain of livestock, poultry and fish. When vitamin B12 deficiency occurs, the use process of sugar in livestock, poultry and fish tissues will be impeded, and livestock, poultry and fish will show loss of appetite, slow growth or weightlessness, severe wasting, pica and extreme anemia. So vitamin B12 additives as livestock, poultry, fish feed essential ingredients, in the feed industry has a wide range of applications.

　　2· Objective of production process innovation of vitamin B12 additive

　　①The content of active ingredients is uniform. According to the needs of customers, The company produces and processes vitamin B12 additives, the final product vitamin B12 content of the additive is 0.1%-1%, the effective ingredient content is uniform.②Good shape preserving property. The vitamin B12 additive of Weikeda company is not easy to dissolve. After being added into feed products, it can remain insoluble even under water immersion for a long time. Therefore, The Vitamin B12 additive of Weikeda Company can not only be used in general livestock and poultry breeding, but also can be used in aquaculture.③Good at inducing food. The vitamin B12 additive of Weikeda company has an appropriate high temperature effect in the processing, which promotes the production of some flavorings in the material and increases the feeding attraction of the feed for livestock, poultry and fish. The vitamin B12 additive of Weikeda company increases the feeding speed of livestock, poultry and fish, which can effectively increase the feed intake of livestock, poultry and fish.④Convenient for breeding management. The vitamin B12 additive material of Weikeda company is uniform, which can accurately understand the intake amount of livestock, poultry and fish during breeding, so as to timely adjust feeding amount and feeding time, save the use of additives, and prevent the waste of B12 additive.⑤Additive safety improved. General additives raw materials, in the transportation, storage and other logistics process, may be infected by bacteria. In the extrusion process of The Vitamin B12 supplement, the high intensity hydrothermal effect effectively removes most of the harmful factors, making the Vitamin B12 supplement of The Vicoda very safe.

　　3 · The production process innovation of vitamin B12 additive

　　3.1 Mixing granulator model selection innovation. Mixing granulator is generally divided into single screw granulator and double screw granulator mixing granulator 2 models. Single screw granulator has poor adaptability to material change and product requirement change. The vitamin B12 additive of Weikeda company needs to produce products with different vitamin B12 content and granularity according to customers' needs, so the single screw granule mixing machine is not suitable. Vikeda innovatively USES twin screw granulator as needed, so that the granulator can be used in a wider range. Due to the assistance of the two screws in the granulator, the direction of the material in the granulator extrusion process is more ideal to control, avoid the reverse gap flow in the single screw granulator, so that the force of the material is balanced, vitamin B12 additive product particle size is uniform. And twin-screw granulator two screw working cleaning each other adhere to the screw material, so twin-screw granulator production material residue is very little, save the use of raw materials.

　　3.2 Innovation of raw material water regulation technology. In order to make the vitamin B12 additive easy to shape, it is necessary to control the moisture of the material when the raw material enters the mixing granulation machine. The material moisture has influence on the yield of vitamin B12 additive, energy consumption during production, product quality of vitamin B12 additive, service life of granulator and working stability of granulator. The moisture content of the vitamin B12 additive increases, and the subsequent steam cost and drying cost increase accordingly. Vitamin B12 additive production raw material needs to have a certain moisture content, so can promote vitamin B12 additive production raw material softening, reduce vitamin B12 additive material to the equipment friction resistance, reduce the driving force requirement of mixing granule machine screw, and reduce the wear and tear of mixing granule machine. Through the technical personnel of Weikeda company, it is considered that the water content of vitamin B12 additive material is 22%-31%, which is the appropriate operating parameter of the granulator.

　　3.3 Wet mixing process. The carrier of vitamin B12 additives is usually corn starch, or calcium carbonate, calcium hydrogen phosphate, mannitol as the carrier according to customer requirements. The corn starch was placed in a granule mixing machine, and then according to the vitamin B12 content required by the customer, the vitamin B12 content of the order was added into the liquid. After stirring for 10 minutes, the material was removed and the vitamin B12 additive was obtained.

　　3.4 Drying process and process innovation. Vitamin B12 additive comes out from mixing granule machine, general moisture content is above 25%. So after leaving the mixing granule machine vitamin B12 additive granule must be dried, remove vitamin B12 additive part of the water. The drying of vitamin B12 additives is usually carried out in two steps: hot air drying and cold air drying. The boiling dryer is used to dry the material with hot air at the air inlet temperature of 120℃ ~ 130℃. Boiling dryer within the range of 120℃ ~ 130℃ drying efficiency is high, and vitamin B12 additive material is not easy to coking. The moisture content of vitamin B12 additive decreased to 14% ~ 18% due to hot air drying. When the air outlet temperature rises from 60 ° C to 80 ° C, set the air inlet temperature at 40 ° C, stop the induced draft fan after 40 minutes, and unload the dried vitamin B12 additive material.

　　It is also one of the important measures to adjust the density of vitamin B12 additive. The company's researchers believe that reducing the degree of evaporation of vitamin B12 supplements can increase the density of vitamin B12 supplements. Adjust the temperature in the screw bore, heating to vaporize water, vitamin B12 additive density decreased; The density of vitamin B12 additive product can be increased by cooling water in the screw chamber to reduce the vaporization strength. Therefore, according to the customer's needs, vitamin B12 additive drying degree control.

　　3.5 Post-treatment process, dry mixing process and final screening. Check the state of the vibrating screen and the screen screen, according to the customer needs to choose the corresponding mesh screen, vitamin B12 additive dry material is added to the vibrating screen, dry material is crushed and mixed with the powder under the screen, mixed with vitamin B12 additive intermediate. The vitamin B12 additive intermediate is placed in the cone mixer, and the solid vitamin B12 formula is added according to the requirements of the customer's order. After stirring for 30 minutes, the vitamin B12 additive mixture is taken out from the bottom of the mixer. Mix the finished product powder, according to customer demand, use the corresponding screen mesh vibrating screen for screening, remove the sundry.

　　3.6 Quality control innovation in packaging and before and after packaging. According to the packaging specifications, accurately weigh and check the vitamin B12 additives, and then pack according to the packaging requirements, that is, double layer polythene bag tie mouth and aluminum foil bag hot seal. The packaging process is critical to the quality control of vitamin B12 additives. No matter whether all the production processes before vitamin B12 additives meet the requirements of vitamin B12 additive processing, the packaging process of vitamin B12 additives should be strengthened to monitor. Quality inspector to vitamin B12 additive products for careful inspection, if found vitamin B12 additive quality problems, need to timely feedback to the vitamin B12 additive production line producers or control, in order to improve the vitamin B12 additive production process, in order to ensure the quality of vitamin B12 additive products. During the packaging of vitamin B12 additives, when the label is added and sealed, it must ensure that there is no production error of vitamin B12 additives, the particle size of vitamin B12 additives meets the requirements, the effective content index of B12 is tested to be qualified, and the packaging weight of vitamin B12 additives is within the error specified range.

　　4· Innovation of quality control in the production process of vitamin B12 additive

　　4.1 Improve and perfect the performance of vitamin B12 additive equipment. Mechanical and electrical equipment has a direct impact on the quality of vitamin B12 additive products. So mixing granule machine, boiling drying machine, sealing machine and other equipment, determines the appearance of vitamin B12 additive products, uniformity and sealing quality. So in the vitamin B12 additive production equipment management, must be responsible to people, strengthen the maintenance of vitamin B12 additive production equipment, improve and improve the performance of vitamin B12 additive production equipment, so that vitamin B12 additive production equipment can be effectively invested in high quality vitamin B12 additive production. In the production of vitamin B12 additives, it is necessary to strictly comply with the production process requirements of vitamin B12 additives. In the production of vitamin B12 additives, reasonable process design and selection of process parameters should be carried out to avoid equipment failure in the production of vitamin B12 additives, reduce the residual materials in the processing process, and better produce qualified vitamin B12 additives products.

　　4.2 Establish a scientific quality control system for vitamin B12 additives. The company needs to develop post responsibility system and production management system for the production personnel of vitamin B12 additives, and constantly improve them. The company also strictly in accordance with the national "feed veterinary drug additive management regulations" and other regulations for production. This allows Vicoda to more effectively and specifically control the quality of vitamin B12 supplements. Through the system to reduce the vitamin B12 additive production process of hidden quality problems, through the quality management system, for vitamin B12 additives in different production links to control, to avoid the quality of vitamin B12 additives problems. According to the different positions of vitamin B12 additive production, The company should define the responsibilities and formulate the corresponding management system. For vitamin B12 additive production equipment operators, from the start of the vitamin B12 additive production equipment order, accurate input, vitamin B12 additive formulation to formulate corresponding management system, and comprehensively in the vitamin B12 additive production process, ensure the production quality control of vitamin B12 supplements.